Connective Issue #35

MIB News
Connective Issue #35

-Volume 35 | July 9, 2025

We’re still feeling the FACTOR love after an incredible 2.5 days of connection and collaboration in Salt Lake City! Stay tuned for the photo album, General Session recordings, and conference proceedings. ITMT, save the date: FACTOR 2026 will be held June 25–27 in Columbus, OH. This Sarcoma Awareness Month, we’re proud to spotlight our partner SPAGN, which unites sarcoma patient voices worldwide to drive patient-centered research and awareness. Medical professionals are invited to TURBO, an educational forum to discuss real-world complex cases - meeting today July 9th at 5p ET. Amidst federal funding uncertainty, MIB Agents Family Funds are proud to announce our largest OutSmarting Osteosarcoma grant cycle yet, $700,000 to support 10 research studies. It's a powerful example of what’s possible when patients and scientists work together to Make It Better.

With hope,

The MIB Agents Team

Ways to Connect this Month

View the Full Calendar

OUR COMMUNITY

Feeling the FACTOR Love

Thank you to everyone who made FACTOR 2025 so special! Each and every one of you was a key ingredient in making this year’s gathering such a meaningful and impactful experience. We’re so grateful for this incredible community. Stay tuned for the full photo album and conference proceedings, including abstracts from our oral and poster presenters. Thanks to the generous support of the Cheung Family, Because of Isaac, we’ll also be sharing recordings of all the scientific panels soon.

Mark your calendars - FACTOR 2026 will take place June 25–27 in Columbus, Ohio!

Spotlight on SPAGN for Sarcoma Awareness Month

What began as a European network of sarcoma patient advocates has grown into a global movement. In honor of Sarcoma Awareness Month, we are honored to spotlight our foundation partner SPAGN. Kathrin Schuster, Executive Director of the Sarcoma Patient Advocacy Global Network (SPAGN), shares the organization’s evolution, impact, and vision for the future. From uniting voices across five continents to shaping patient-centered research and awareness campaigns, SPAGN is proving that global collaboration can drive meaningful change for the sarcoma community.

Learn More About SPAGN

Career Connections

- Division Director, Hematology/Oncology - Iowa Healthcare

- Program Manager, Adolescent and Young Adult Sarcoma - DFCI

- Assistant Professor, Sarcoma - OSHU

- Researcher - Radiation Oncology - The Ohio State University

- Assistant Attending Physician, Sarcoma Medical Oncology Service – MSKCC

If you have a job posting and you would like it included here, please email christina@mibagents.org.

EDUCATION

Share and Discuss Cases at TURBO

TURBO (TUmor Review Board for Osteosarcoma) is a virtual, international tumor board designed to connect physicians treating osteosarcoma with world-leading experts across disciplines. Moderated by Dr. Matteo Trucco from Cleveland Clinic, TURBO provides a unique space to review complex cases, share clinical insights, and foster collaboration among top institutions. Clinicians can present challenging cases and receive multidisciplinary input, while research scientists are invited to attend and gain valuable exposure to real-world clinical decision-making. Participation is free, because better collaboration leads to better care.

Our next meeting is July 9th at 5p ET.

Join TURBO

Osteosarcoma in the News

- Targeting metastasis in paediatric bone sarcomas

- Results of a phase II trial of olaparib in combination with ceralasertib in patients with recurrent and unresectable osteosarcoma

- Comprehensive investigation of DNA damage repair genes in children with cancer identifies SMARCAL1 as novel osteosarcoma predisposition gene

- Identification and validation of SAC3D1 as a prognostic biomarker promoting the development of osteosarcoma

- Targeting Regnase-1 unleashes CAR T cell antitumor activity for osteosarcoma and creates a proinflammatory tumor microenvironment

- Repurposing Romidepsin for Osteosarcoma: Screening FDA-Approved Oncology Drugs with Three-Dimensional Osteosarcoma Spheroids

PROGRAMS

Join Gamer Agents

Online gaming is a lifeline for many young people who feel isolated during treatment.  Our young adult Lead Gamer Agents are trained to game with OsteoWarriors in treatment, surviving OsteoWarriors, and siblings.   We have gamers on all platforms. Gamer Agents is more than a way to have fun; it provides a safe space for gamers to be themselves and connect with kids like them, who get it!

Game With Us

RESEARCH

OutSmarting Osteosarcoma 2025 Grant Recipients

We're proud to announce that MIB Agents has awarded $700,000 this year in OutSmarting Osteosarcoma grants to 10 scientists advancing bold, patient-centered osteosarcoma research. These grants are powered by MIB Agents Family Funds and partner foundations, families honoring OsteoWarriors and OsteoAngels through action. Learn more about this year's inspiring recipients and the families behind the funding.

Learn More About Our 2025 OutSmarting Recipients

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